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Stabilization of Microtubules by Taxane Diterpenoids: Insight from Docking and MD simulations
Microtubules are formed from the molecules of tubulin, whose dynamics is important for many functions in a cell, the most dramatic of which is mitosis. Taxol is known to interact within a specific site on tubulin and also believed to block cell-cycle progression during mitosis by binding to and stab...
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| 出版年: | J Biol Phys |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Netherlands
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366434/ https://ncbi.nlm.nih.gov/pubmed/25542396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-014-9369-5 |
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