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Stabilization of Microtubules by Taxane Diterpenoids: Insight from Docking and MD simulations

Microtubules are formed from the molecules of tubulin, whose dynamics is important for many functions in a cell, the most dramatic of which is mitosis. Taxol is known to interact within a specific site on tubulin and also believed to block cell-cycle progression during mitosis by binding to and stab...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Phys
Main Authors: Yadava, Umesh, Gupta, Hariom, Roychoudhury, Mihir
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer Netherlands 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366434/
https://ncbi.nlm.nih.gov/pubmed/25542396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-014-9369-5
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