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Hippocampal Endosomal, Lysosomal and Autophagic Dysregulation in Mild Cognitive Impairment: Correlation with Aβ and Tau Pathology

Endosomal-lysosomal and autophagic dysregulation occurs in the hippocampus in prodromal Alzheimer disease (AD), but its relationship with β-amyloid (Aβ) and tau pathology remain unclear. To investigate this issue, we performed immunoblot analysis of hippocampal homogenates from cases with an antemor...

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Dades bibliogràfiques
Publicat a:J Neuropathol Exp Neurol
Autors principals: Perez, Sylvia E., He, Bin, Nadeem, Muhammad, Wuu, Joanne, Ginsberg, Stephen D., Ikonomovic, Milos D., Mufson, Elliott J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366294/
https://ncbi.nlm.nih.gov/pubmed/25756588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000179
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