Detection of BRAF V600 Mutations in Melanoma: Evaluation of Concordance between the Cobas® 4800 BRAF V600 Mutation Test and the Methods Used in French National Cancer Institute (INCa) Platforms in a Real-Life Setting

Vemurafenib is approved for the treatment of metastatic melanoma in patients with BRAF V600 mutation. In pivotal clinical trials, BRAF testing has always been done with the approved cobas 4800 BRAF test. In routine practice, several methods are available and are used according to the laboratories us...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mourah, Samia, Denis, Marc G., Narducci, Fabienne Escande, Solassol, Jérôme, Merlin, Jean-Louis, Sabourin, Jean-Christophe, Scoazec, Jean-Yves, Ouafik, L’Houcine, Emile, Jean-François, Heller, Remy, Souvignet, Claude, Bergougnoux, Loïc, Merlio, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366252/
https://ncbi.nlm.nih.gov/pubmed/25789737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120232
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