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Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein
Aggregation of α-synuclein (α-syn) is associated with the development of a number of neurodegenerative diseases, including Parkinson’s disease (PD). The formation of α-syn aggregates results from aberrant accumulation of misfolded α-syn and insufficient or impaired activity of the two main intracell...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366176/ https://ncbi.nlm.nih.gov/pubmed/25790376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120819 |
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