In Vivo Assessment of NS1-Truncated Influenza Virus with a Novel SLSYSINWRH Motif as a Self-Adjuvanting Live Attenuated Vaccine

Mutants of influenza virus that encode C-terminally truncated NS1 proteins (NS1-truncated mutants) characteristically induce high interferon responses. The dual activity of interferon in blocking virus replication and enhancing the development of adaptive immune responses makes these mutants promisi...

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Vydáno v:PLoS One
Hlavní autoři: Ngunjiri, John M., Ali, Ahmed, Boyaka, Prosper, Marcus, Philip I., Lee, Chang-Won
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366013/
https://ncbi.nlm.nih.gov/pubmed/25790187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118934
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