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Association between Interferon Response and Protective Efficacy of NS1-Truncated Mutants as Influenza Vaccine Candidates in Chickens

Influenza virus mutants that encode C-terminally truncated NS1 proteins (NS1-truncated mutants) are attractive candidates for avian live attenuated influenza vaccine (LAIV) development because they are both attenuated and immunogenic in chickens. We previously showed that a high protective efficacy...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Jang, Hyesun, Ngunjiri, John M., Lee, Chang-Won
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892592/
https://ncbi.nlm.nih.gov/pubmed/27257989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156603
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