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Inhibition of the Cardiomyocyte-Specific Kinase TNNI3K Limits Oxidative Stress, Injury, and Adverse Remodeling in the Ischemic Heart

Percutaneous coronary intervention is first-line therapy for acute coronary syndromes (ACS) but can promote cardiomyocyte death and cardiac dysfunction via reperfusion injury, a phenomenon driven in large part by oxidative stress. Therapies to limit this progression have proven elusive, with no majo...

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Detaylı Bibliyografya
Yayımlandı:Sci Transl Med
Asıl Yazarlar: Vagnozzi, Ronald J., Gatto, Gregory J., Kallander, Lara S., Hoffman, Nicholas E., Mallilankaraman, Karthik, Ballard, Victoria L. T., Lawhorn, Brian G., Stoy, Patrick, Philp, Joanne, Graves, Alan P., Naito, Yoshiro, Lepore, John J., Gao, Erhe, Madesh, Muniswamy, Force, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365498/
https://ncbi.nlm.nih.gov/pubmed/24132636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006479
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