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Understanding the effect of alternative splicing in the folding and function of the second PDZ from Protein Tyrosine Phosphatase-BL

PDZ domains are the most prominent biological structural domains involved in protein-protein interactions in the human cell. The second PDZ domain of the protein tyrosine phosphatase BL (PDZ2) interacts and binds the C-termini of the tumour suppressor protein APC and of the LIM domain-containing pro...

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Publicat a:Sci Rep
Autors principals: Di Silvio, Eva, Toto, Angelo, Bonetti, Daniela, Morrone, Angela, Gianni, Stefano
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365404/
https://ncbi.nlm.nih.gov/pubmed/25788329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09299
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