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Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2

Gab2 is a large disordered protein that regulates several cellular signalling pathways and is overexpressed in different forms of cancer. Because of its disordered nature, a detailed characterization of the mechanisms of recognition between Gab2 and its physiological partners is particularly difficu...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Toto, Angelo, Bonetti, Daniela, De Simone, Alfonso, Gianni, Stefano
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669894/
https://ncbi.nlm.nih.gov/pubmed/29137268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19323
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