Targeting the Interaction between the SH3 Domain of Grb2 and Gab2

Gab2 is a scaffolding protein, overexpressed in many types of cancers, that plays a key role in the formation of signaling complexes involved in cellular proliferation, migration, and differentiation. The interaction between Gab2 and the C-terminal SH3 domain of the protein Grb2 is crucial for the a...

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Publicado en:Cells
Autores principales: Malagrinò, Francesca, Coluccia, Antonio, Bufano, Marianna, Regina, Giuseppe La, Puxeddu, Michela, Toto, Angelo, Visconti, Lorenzo, Paone, Alessio, Magnifico, Maria Chiara, Troilo, Francesca, Cutruzzolà, Francesca, Silvestri, Romano, Gianni, Stefano
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695167/
https://ncbi.nlm.nih.gov/pubmed/33171874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112435
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