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Inhibition of Osteoclast Activation by Phloretin through Disturbing αvβ3 Integrin-c-Src Pathway

This study was to explore the sequential signaling of disorganization of the actin cytoskeletal architecture by phloretin. RAW 264.7 macrophages were incubated with 1–20 μM phloretin for 5 days in the presence of RANKL. C57BL/6 mice were ovariectomized (OVX) and orally treated with 10 mg/kg phloreti...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Biomed Res Int
Main Authors: Lee, Eun-Jung, Kim, Jung-Lye, Gong, Ju-Hyun, Park, Sin-Hye, Kang, Young-Hee
פורמט: Artigo
שפה:Inglês
יצא לאור: Hindawi Publishing Corporation 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365379/
https://ncbi.nlm.nih.gov/pubmed/25834823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/680145
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