Molecular and In Vivo Characterization of Cancer-Propagating Cells Derived from MYCN-Dependent Medulloblastoma

Medulloblastoma (MB) is the most common malignant pediatric brain tumor. While the pathways that are deregulated in MB remain to be fully characterized, amplification and/or overexpression of the MYCN gene, which is has a critical role in cerebellar development as a regulator of neural progenitor ce...

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Bibliographic Details
Published in:PLoS One
Main Authors: Ahmad, Zai, Jasnos, Lukasz, Gil, Veronica, Howell, Louise, Hallsworth, Albert, Petrie, Kevin, Sawado, Tomoyuki, Chesler, Louis
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365014/
https://ncbi.nlm.nih.gov/pubmed/25785590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119834
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