Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human

Genome maintenance (GM) is an essential defense system against aging and cancer, as both are characterized by increased genome instability. Here, we compared the copy number variation and mutation rate of 518 GM-associated genes in the naked mole rat (NMR), mouse, and human genomes. GM genes appeare...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: MacRae, Sheila L, Zhang, Quanwei, Lemetre, Christophe, Seim, Inge, Calder, Robert B, Hoeijmakers, Jan, Suh, Yousin, Gladyshev, Vadim N, Seluanov, Andrei, Gorbunova, Vera, Vijg, Jan, Zhang, Zhengdong D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BlackWell Publishing Ltd 2015
Gaiak:
Short Takes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364841/
https://ncbi.nlm.nih.gov/pubmed/25645816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12314
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