A Novel Class of Mitochondria-Targeted Soft Electrophiles Modifies Mitochondrial Proteins and Inhibits Mitochondrial Metabolism in Breast Cancer Cells through Redox Mechanisms

Despite advances in screening and treatment over the past several years, breast cancer remains a leading cause of cancer-related death among women in the United States. A major goal in breast cancer treatment is to develop safe and clinically useful therapeutic agents that will prevent the recurrenc...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Vayalil, Praveen K., Oh, Joo-Yeun, Zhou, Fen, Diers, Anne R., Smith, M. Ryan, Golzarian, Hafez, Oliver, Patsy G., Smith, Robin A. J., Murphy, Michael P., Velu, Sadanandan E., Landar, Aimee
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2015
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364723/
https://ncbi.nlm.nih.gov/pubmed/25785718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120460
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