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Mitochondrial targeting of the electrophilic lipid 15-deoxy-Δ(12,14)-Prostaglandin J(2) increases apoptotic efficacy via redox cell signaling mechanisms
Prototypical electrophiles such as the lipid 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) are well recognized for their therapeutic potential. Electrophiles modify signaling proteins in both the cytosol and mitochondrion which results in diverse cellular responses including cytoprotective effec...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079364/ https://ncbi.nlm.nih.gov/pubmed/19916962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091293 |
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