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Accumulation of 15-deoxy-Δ(12,14)-prostaglandin J(2) adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defense induction
The cyclooxygenase (COX) pathway generates the reactive lipid electrophile 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)), which forms covalent protein adducts that modulate cell signaling pathways. It has been shown that this regulates important biological responses, including protection against...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683789/ https://ncbi.nlm.nih.gov/pubmed/18237271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/bj20071189 |
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