Induction of the permeability transition and cytochrome c release by 15-deoxy-Δ(12,14)-prostaglandin J(2) in mitochondria

The electrophilic lipid 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) is known to allow adaptation to oxidative stress in cells at low concentrations and apoptosis at high levels. The mechanisms leading to adaptation involve the covalent modification of regul-atory proteins, such as Keap1, and a...

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Detalhes bibliográficos
Main Authors: Landar, Aimee, Shiva, Sruti, Levonen, Anna-Liisa, Oh, Joo-Yeun, Zaragoza, Corinne, Johnson, Michelle S., Darley-Usmar, Victor M.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386016/
https://ncbi.nlm.nih.gov/pubmed/16268779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051259
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