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Electrophilic Lipid Mediator 15-Deoxy-Δ(12,14)-Prostaglandin J(2) Modifies Glucocorticoid Signaling via Receptor SUMOylation
Cortisol, the central stress hormone in humans, activates the glucocorticoid receptor (GR). Anti-inflammatory effects are the most important pharmaceutical effects mediated by the GR. Inasmuch as electrophilic cyclopentenone prostaglandin 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) has potent...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135560/ https://ncbi.nlm.nih.gov/pubmed/24980431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00748-14 |
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