A Novel Class of Mitochondria-Targeted Soft Electrophiles Modifies Mitochondrial Proteins and Inhibits Mitochondrial Metabolism in Breast Cancer Cells through Redox Mechanisms

Despite advances in screening and treatment over the past several years, breast cancer remains a leading cause of cancer-related death among women in the United States. A major goal in breast cancer treatment is to develop safe and clinically useful therapeutic agents that will prevent the recurrenc...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Vayalil, Praveen K., Oh, Joo-Yeun, Zhou, Fen, Diers, Anne R., Smith, M. Ryan, Golzarian, Hafez, Oliver, Patsy G., Smith, Robin A. J., Murphy, Michael P., Velu, Sadanandan E., Landar, Aimee
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364723/
https://ncbi.nlm.nih.gov/pubmed/25785718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120460
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires