Variable Processing and Cross-presentation of HIV by Dendritic Cells and Macrophages Shapes CTL Immunodominance and Immune Escape

Dendritic cells (DCs) and macrophages (Møs) internalize and process exogenous HIV-derived antigens for cross-presentation by MHC-I to cytotoxic CD8(+) T cells (CTL). However, how degradation patterns of HIV antigens in the cross-presentation pathways affect immunodominance and immune escape is poorl...

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Publicat a:PLoS Pathog
Autors principals: Dinter, Jens, Duong, Ellen, Lai, Nicole Y., Berberich, Matthew J., Kourjian, Georgio, Bracho-Sanchez, Edith, Chu, Duong, Su, Hang, Zhang, Shao Chong, Le Gall, Sylvie
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364612/
https://ncbi.nlm.nih.gov/pubmed/25781895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004725
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