Different antigen processing activities in dendritic cells, macrophages and monocytes lead to uneven production of HIV epitopes and affect CTL recognition

Dendritic cells (DCs), macrophages (MPs) and monocytes are permissive to HIV. Whether they similarly process and present HIV epitopes to HIV-specific CD8 T cells is unknown despite the critical role of peptide processing and presentation for recognition and clearance of infected cells. Cytosolic pep...

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Main Authors: Dinter, Jens, Gourdain, Pauline, Lai, Nicole Y., Duong, Ellen, Bracho-Sanchez, Edith, Rucevic, Marijana, Liebesny, Paul H., Xu, Yang, Shimada, Mariko, Ghebremichael, Musie, Kavanagh, Daniel G., Le Gall, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201977/
https://ncbi.nlm.nih.gov/pubmed/25230751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400491
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