Different antigen processing activities in dendritic cells, macrophages and monocytes lead to uneven production of HIV epitopes and affect CTL recognition

Dendritic cells (DCs), macrophages (MPs) and monocytes are permissive to HIV. Whether they similarly process and present HIV epitopes to HIV-specific CD8 T cells is unknown despite the critical role of peptide processing and presentation for recognition and clearance of infected cells. Cytosolic pep...

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Hauptverfasser: Dinter, Jens, Gourdain, Pauline, Lai, Nicole Y., Duong, Ellen, Bracho-Sanchez, Edith, Rucevic, Marijana, Liebesny, Paul H., Xu, Yang, Shimada, Mariko, Ghebremichael, Musie, Kavanagh, Daniel G., Le Gall, Sylvie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201977/
https://ncbi.nlm.nih.gov/pubmed/25230751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400491
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