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A real-time killing assay to follow viral epitope presentation to CD8 T cells
The ability of cytotoxic T lymphocytes (CTL) to clear virus-infected cells requires the presentation of viral peptides intracellularly processed and displayed by major histocompatibility complex class I. Assays to measure CTL-mediated killing often use peptides exogenously added onto target cells –w...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845008/ https://ncbi.nlm.nih.gov/pubmed/24060536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2013.09.009 |
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