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A real-time killing assay to follow viral epitope presentation to CD8 T cells

The ability of cytotoxic T lymphocytes (CTL) to clear virus-infected cells requires the presentation of viral peptides intracellularly processed and displayed by major histocompatibility complex class I. Assays to measure CTL-mediated killing often use peptides exogenously added onto target cells –w...

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Detalhes bibliográficos
Main Authors: Gourdain, Pauline, Boucau, Julie, Kourjian, Georgio, Lai, Nicole, Duong, Ellen, Le Gall, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845008/
https://ncbi.nlm.nih.gov/pubmed/24060536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2013.09.009
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