The effect of erlotinib on EGFR and downstream signaling in oral cavity squamous cell carcinoma

PURPOSE: To determine if there are differences in biomarker modulation and EGFR degradation between tumor and the normal mucosa following treatment with an EGFR inhibitor, erlotinib, in head and neck cancer. METHODS: Patients with primary oral cavity squamous cell cancers received a course of erloti...

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Veröffentlicht in:Head Neck
Hauptverfasser: Tsien, Christina I., Nyati, Mukesh K., Ahsan, Aarif, Ramanand, Susmita G, Chepeha, Douglas B., Worden, Francis P., Helman, Joseph I., D’Silva, Nisha, Bradford, Carol R., Wolf, Gregory T., Lawrence, Theodore S., Eisbruch, Avraham
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364542/
https://ncbi.nlm.nih.gov/pubmed/22907806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.23128
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