SIRT3 DEACETYLATES AND INCREASES PYRUVATE DEHYDROGENASE ACTIVITY IN CANCER CELLS

Pyruvate dehydrogenase E1 alpha (PDHE1α or PDHA1) is the first component enzyme of the pyruvate dehydrogenase (PDH) complex (PDC) that transforms pyruvate, via pyruvate decarboxylation, into acetyl-CoA that is subsequently used by both the citric acid cycle and oxidative phosphorylation to generate...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Free Radic Biol Med
Egile Nagusiak: Ozden, Ozkan, Park, Seong-Hoon, Wagner, Brett A., Song, Ha Yong, Zhu, Yueming, Vassilopoulos, Athanassios, Jung, Barbara, Buettner, Garry R., Gius, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364304/
https://ncbi.nlm.nih.gov/pubmed/25152236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.08.001
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