A mutant BRAF V600E-specific immunohistochemical assay: correlation with molecular mutation status and clinical outcome in colorectal cancer

The B-type Raf kinase (BRAF) V600E mutation is a well-established biomarker for poor prognosis in metastatic colorectal cancer (mCRC) and is a highly attractive drug target. A barrier to the development of new therapies targeting BRAF V600E in mCRC is the low prevalence of mutations (approximately 1...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Target Oncol
Main Authors: Day, Fiona, Muranyi, Andrea, Singh, Shalini, Shanmugam, Kandavel, Williams, David, Byrne, David, Pham, Kym, Palmieri, Michelle, Tie, Jeanne, Grogan, Thomas, Gibbs, Peter, Sieber, Oliver, Waring, Paul, Desai, Jayesh
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363480/
https://ncbi.nlm.nih.gov/pubmed/24859797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-014-0319-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados