Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway

Lignende værker

• MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors
  af: Sells, Todd B., et al.
  Udgivet: (2015)
• Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway
  af: Niu NK, et al.
  Udgivet: (2015-03-01)
• The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G(2)/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells
  af: Li, Jin-Ping, et al.
  Udgivet: (2015)
• A SILAC-based proteomics elicits the molecular interactome of alisertib (MLN8237) in human erythroleukemia K562 cells
  af: Shu, Li-Ping, et al.
  Udgivet: (2015)
• Effect of Food on the Pharmacokinetics of the Investigational Aurora A Kinase Inhibitor Alisertib (MLN8237) in Patients with Advanced Solid Tumors
  af: Falchook, Gerald S., et al.
  Udgivet: (2015)