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A SILAC-based proteomics elicits the molecular interactome of alisertib (MLN8237) in human erythroleukemia K562 cells

Alisertib (MLN8237, ALS), an Aurora kinase A (AURKA) inhibitor, exerts potent anti-tumor effects in the treatment of solid tumor and hematologic malignancies in preclinical and clinical studies. However, the fully spectrum of molecular targets of ALS and its anticancer effect in the treatment of chr...

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Publicado en:Am J Transl Res
Autores principales: Shu, Li-Ping, Zhou, Zhi-Wei, Zi, Dan, He, Zhi-Xu, Zhou, Shu-Feng
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697722/
https://ncbi.nlm.nih.gov/pubmed/26807190
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