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Effects of TP53 Mutational Status on Gene Expression Patterns Across Ten Human Cancer Types

Mutations in the TP53 tumor suppressor gene occur in half of all human cancers, indicating its critical importance in inhibiting cancer development. Despite extensive studies, the mechanisms by which mutant p53 enhances tumor progression remain only partially understood. Here, using data from The Ca...

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Dettagli Bibliografici
Pubblicato in:J Pathol
Autori principali: Parikh, Neha, Hilsenbeck, Susan, Creighton, Chad J., Dayaram, Tajhal, Shuck, Ryan, Shinbrot, Eve, Xi, Liu, Gibbs, Richard A., Wheeler, David A., Donehower, Lawrence A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362779/
https://ncbi.nlm.nih.gov/pubmed/24374933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4321
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