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Effects of TP53 Mutational Status on Gene Expression Patterns Across Ten Human Cancer Types

Mutations in the TP53 tumor suppressor gene occur in half of all human cancers, indicating its critical importance in inhibiting cancer development. Despite extensive studies, the mechanisms by which mutant p53 enhances tumor progression remain only partially understood. Here, using data from The Ca...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Parikh, Neha, Hilsenbeck, Susan, Creighton, Chad J., Dayaram, Tajhal, Shuck, Ryan, Shinbrot, Eve, Xi, Liu, Gibbs, Richard A., Wheeler, David A., Donehower, Lawrence A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362779/
https://ncbi.nlm.nih.gov/pubmed/24374933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4321
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