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Enhanced inflammation and attenuated tumor suppressor pathways are associated with oncogene‐induced lung tumors in aged mice
Aging is often accompanied by a dramatic increase in cancer susceptibility. To gain insights into how aging affects tumor susceptibility, we generated a conditional mouse model in which oncogenic Kras (G12D) was activated specifically in lungs of young (3–5 months) and old (19–24 months) mice. Activ...
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| Publicat a: | Aging Cell |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771401/ https://ncbi.nlm.nih.gov/pubmed/29047229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12691 |
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