Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

The TP53 tumor suppressor gene is frequently mutated in human cancers. Analysis of five data platforms in 10,225 patient samples from 32 cancers reported by The Cancer Genome Atlas (TCGA) has enabled comprehensive assessment of p53 pathway involvement in these cancers. Over 91% of TP53 mutant cancer...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Donehower, Lawrence A., Soussi, Thierry, Korkut, Anil, Liu, Yuexin, Schultz, Andre, Cardenas, Maria, Li, Xubin, Babur, Ozgun, Hsu, Teng-Kuei, Lichtarge, Olivier, Weinstein, John, Akbani, Rehan, Wheeler, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546539/
https://ncbi.nlm.nih.gov/pubmed/31365877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.001
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