Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

The TP53 tumor suppressor gene is frequently mutated in human cancers. Analysis of five data platforms in 10,225 patient samples from 32 cancers reported by The Cancer Genome Atlas (TCGA) has enabled comprehensive assessment of p53 pathway involvement in these cancers. Over 91% of TP53 mutant cancer...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Donehower, Lawrence A., Soussi, Thierry, Korkut, Anil, Liu, Yuexin, Schultz, Andre, Cardenas, Maria, Li, Xubin, Babur, Ozgun, Hsu, Teng-Kuei, Lichtarge, Olivier, Weinstein, John, Akbani, Rehan, Wheeler, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546539/
https://ncbi.nlm.nih.gov/pubmed/31365877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.001
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky