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A PAI-1 mutant retards diabetic nephropathy in db/db mice through protecting podocytes
PAI-1R, a mutant plasminogen activator inhibitor (PAI-1) that reduces endogenous PAI-1 activity has been shown to inhibit albuminuria and reduce glomerulosclerosis in experimental diabetes. The mechanism of albuminuria reduction is unclear. This study sought to determine whether the administration o...
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| Publicado no: | Exp Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362754/ https://ncbi.nlm.nih.gov/pubmed/24443353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2013.077610 |
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