Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice

Impaired endothelial nitric oxide synthase (eNOS) activity may be involved in the pathogenesis of diabetic nephropathy. To test this, we used the type 2 diabetic db/db mouse (BKS background) model and found impaired eNOS dimerization and phosphorylation along with moderate glomerular mesangial expan...

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Main Authors: Cheng, Huifang, Wang, Hanmin, Fan, Xiaofeng, Paueksakon, Paisit, Harris, Raymond C
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473143/
https://ncbi.nlm.nih.gov/pubmed/22785174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.248
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