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Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice
Impaired endothelial nitric oxide synthase (eNOS) activity may be involved in the pathogenesis of diabetic nephropathy. To test this, we used the type 2 diabetic db/db mouse (BKS background) model and found impaired eNOS dimerization and phosphorylation along with moderate glomerular mesangial expan...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3473143/ https://ncbi.nlm.nih.gov/pubmed/22785174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.248 |
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