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Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors

Dengue virus (DENV) is the most significant human arboviral pathogen and causes ∼400 million infections in humans each year. In previous work, we observed that mast cells (MC) mediate vascular leakage during DENV infection in mice and that levels of MC activation are correlated with disease severity...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Syenina, Ayesa, Jagaraj, Cyril J, Aman, Siti AB, Sridharan, Aishwarya, St John, Ashley L
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362203/
https://ncbi.nlm.nih.gov/pubmed/25783751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05291
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