Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors

Dengue virus (DENV) is the most significant human arboviral pathogen and causes ∼400 million infections in humans each year. In previous work, we observed that mast cells (MC) mediate vascular leakage during DENV infection in mice and that levels of MC activation are correlated with disease severity...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Syenina, Ayesa, Jagaraj, Cyril J, Aman, Siti AB, Sridharan, Aishwarya, St John, Ashley L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2015
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362203/
https://ncbi.nlm.nih.gov/pubmed/25783751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05291
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