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Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability

Dengue virus (DENV), an arbovirus, strongly activates mast cells (MCs), which are key immune cells for pathogen immune surveillance. In animal models, MCs promote clearance of local peripheral DENV infections but, conversely, also promote pathological vascular leakage when widely activated during sy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Viruses
Hauptverfasser: Syenina, Ayesa, Saron, Wilfried A. A., Jagaraj, Cyril J., Bibi, Siham, Arock, Michel, Gubler, Duane J., Rathore, Abhay P. S., Abraham, Soman N., St. John, Ashley L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761533/
https://ncbi.nlm.nih.gov/pubmed/33276578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12121379
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