Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability

Dengue virus (DENV), an arbovirus, strongly activates mast cells (MCs), which are key immune cells for pathogen immune surveillance. In animal models, MCs promote clearance of local peripheral DENV infections but, conversely, also promote pathological vascular leakage when widely activated during sy...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Syenina, Ayesa, Saron, Wilfried A. A., Jagaraj, Cyril J., Bibi, Siham, Arock, Michel, Gubler, Duane J., Rathore, Abhay P. S., Abraham, Soman N., St. John, Ashley L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761533/
https://ncbi.nlm.nih.gov/pubmed/33276578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12121379
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