Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability

Dengue virus (DENV), an arbovirus, strongly activates mast cells (MCs), which are key immune cells for pathogen immune surveillance. In animal models, MCs promote clearance of local peripheral DENV infections but, conversely, also promote pathological vascular leakage when widely activated during sy...

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Publicat a:Viruses
Autors principals: Syenina, Ayesa, Saron, Wilfried A. A., Jagaraj, Cyril J., Bibi, Siham, Arock, Michel, Gubler, Duane J., Rathore, Abhay P. S., Abraham, Soman N., St. John, Ashley L.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761533/
https://ncbi.nlm.nih.gov/pubmed/33276578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12121379
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