Fingolimod Prevents Blood-Brain Barrier Disruption Induced by the Sera from Patients with Multiple Sclerosis

OBJECTIVE: Effect of fingolimod in multiple sclerosis (MS) is thought to involve the prevention of lymphocyte egress from lymphoid tissues, thereby reducing autoaggressive lymphocyte infiltration into the central nervous system across blood-brain barrier (BBB). However, brain microvascular endotheli...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nishihara, Hideaki, Shimizu, Fumitaka, Sano, Yasuteru, Takeshita, Yukio, Maeda, Toshihiko, Abe, Masaaki, Koga, Michiaki, Kanda, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361641/
https://ncbi.nlm.nih.gov/pubmed/25774903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121488
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