Fingolimod promotes blood–nerve barrier properties in vitro

OBJECTIVE: The main effect of fingolimod is thought to be functional antagonism of lymphocytic S1P1 receptors and the prevention of lymphocyte egress from lymphoid tissues, thereby reducing lymphocyte infiltration into the nervous system. However, a growing number of reports suggest that fingolimod...

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Bibliographic Details
Published in:Brain Behav
Main Authors: Nishihara, Hideaki, Maeda, Toshihiko, Sano, Yasuteru, Ueno, Maho, Okamoto, Nana, Takeshita, Yukio, Shimizu, Fumitaka, Koga, Michiaki, Kanda, Takashi
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893339/
https://ncbi.nlm.nih.gov/pubmed/29670818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.924
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