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The Dual Effects of B Cell Depletion on Antigen-Specific T Cells in BDC2.5NOD Mice
B cells play a critical role in the pathogenesis of autoimmune diabetes. To investigate the mechanisms by which B cell depletion therapy attenuates islet β cell loss and particularly to examine the effect of B cells on both diabetogenic and regulatory Ag-specific T cells, we generated a transgenic B...
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| Publicat a: | J Immunol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361183/ https://ncbi.nlm.nih.gov/pubmed/22490442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103055 |
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