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Arrestin-3-dependent activation of c-Jun N-terminal kinases (JNKs)

Only one out of four arrestin subtypes expressed in mammals, arrestin-3, facilitates the activation of JNK family kinases. Here we describe two different paradigms that allow the elucidation of the mechanisms involved. One is based on reconstitution of signaling modules from purified proteins: arres...

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Détails bibliographiques
Publié dans:Curr Protoc Pharmacol
Auteurs principaux: Zhan, Xuanzhi, Kook, Seunghyi, Kaoud, Tamer S., Dalby, Kevin N., Gurevich, Eugenia V., Gurevich, Vsevolod V.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361079/
https://ncbi.nlm.nih.gov/pubmed/25737158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471141755.ph0212s68
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