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Arrestin-3-dependent activation of c-Jun N-terminal kinases (JNKs)

Only one out of four arrestin subtypes expressed in mammals, arrestin-3, facilitates the activation of JNK family kinases. Here we describe two different paradigms that allow the elucidation of the mechanisms involved. One is based on reconstitution of signaling modules from purified proteins: arres...

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Bibliographic Details
Published in:Curr Protoc Pharmacol
Main Authors: Zhan, Xuanzhi, Kook, Seunghyi, Kaoud, Tamer S., Dalby, Kevin N., Gurevich, Eugenia V., Gurevich, Vsevolod V.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361079/
https://ncbi.nlm.nih.gov/pubmed/25737158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471141755.ph0212s68
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