Increased IL-6 Expression in Osteoclasts Is Necessary But Not Sufficient for the Development of Paget’s Disease of Bone

Measles virus nucleocapsid protein (MVNP) expression in osteoclasts (OCLs) and mutation of the SQSTM1 (p62) gene contribute to the increased OCL activity in Paget’s disease (PD). OCLs expressing MVNP display many of the features of PD OCLs. Interleukin-6 (IL-6) production is essential for the pageti...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Bone Miner Res
Main Authors: Teramachi, Jumpei, Zhou, Hua, Subler, Mark A, Kitagawa, Yukiko, Galson, Deborah L, Dempster, David W, Windle, Jolene J, Kurihara, Noriyoshi, Roodman, G David
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361000/
https://ncbi.nlm.nih.gov/pubmed/24339057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2158
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki