Increased IL-6 Expression in Osteoclasts Is Necessary But Not Sufficient for the Development of Paget’s Disease of Bone

Measles virus nucleocapsid protein (MVNP) expression in osteoclasts (OCLs) and mutation of the SQSTM1 (p62) gene contribute to the increased OCL activity in Paget’s disease (PD). OCLs expressing MVNP display many of the features of PD OCLs. Interleukin-6 (IL-6) production is essential for the pageti...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Bone Miner Res
Main Authors: Teramachi, Jumpei, Zhou, Hua, Subler, Mark A, Kitagawa, Yukiko, Galson, Deborah L, Dempster, David W, Windle, Jolene J, Kurihara, Noriyoshi, Roodman, G David
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361000/
https://ncbi.nlm.nih.gov/pubmed/24339057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2158
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares