Discovery of Potent Hexapeptide Agonists to Human Neuromedin U Receptor 1 and Identification of Their Serum Metabolites

[Image: see text] Neuromedin U (NMU) and S (NMS) display various physiological activities, including an anorexigenic effect, and share a common C-terminal heptapeptide-amide sequence that is necessary to activate two NMU receptors (NMUR1 and NMUR2). On the basis of this knowledge, we recently develo...

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Bibliografske podrobnosti
izdano v:ACS Med Chem Lett
Main Authors: Takayama, Kentaro, Mori, Kenji, Sohma, Yuko, Taketa, Koji, Taguchi, Akihiro, Yakushiji, Fumika, Minamino, Naoto, Miyazato, Mikiya, Kangawa, Kenji, Hayashi, Yoshio
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2015
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360155/
https://ncbi.nlm.nih.gov/pubmed/25815150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500494j
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