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Expression of a dominant negative PKA mutation in the kidney elicits a diabetes insipidus phenotype
PKA plays a critical role in water excretion through regulation of the production and action of the antidiuretic hormone arginine vasopressin (AVP). The AVP prohormone is produced in the hypothalamus, where its transcription is regulated by cAMP. Once released into the circulation, AVP stimulates an...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360038/ https://ncbi.nlm.nih.gov/pubmed/25587115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00222.2014 |
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