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Expression of a dominant negative PKA mutation in the kidney elicits a diabetes insipidus phenotype

PKA plays a critical role in water excretion through regulation of the production and action of the antidiuretic hormone arginine vasopressin (AVP). The AVP prohormone is produced in the hypothalamus, where its transcription is regulated by cAMP. Once released into the circulation, AVP stimulates an...

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書目詳細資料
發表在:Am J Physiol Renal Physiol
Main Authors: Gilbert, Merle L., Yang, Linghai, Su, Thomas, McKnight, G. Stanley
格式: Artigo
語言:Inglês
出版: American Physiological Society 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360038/
https://ncbi.nlm.nih.gov/pubmed/25587115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00222.2014
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