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Selective Expression of a Dominant-Negative Type Ια PKA Regulatory Subunit in Striatal Medium Spiny Neurons Impairs Gene Expression and Leads to Reduced Feeding and Locomotor Activity
Striatal medium spiny neurons (MSNs) mediate many of the physiological effects of dopamine, including the regulation of feeding and motor behaviors. Dopaminergic inputs from the midbrain modulate MSN excitability through pathways that involve cAMP and protein kinase A (PKA), but the physiological ro...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Society for Neuroscience
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972716/ https://ncbi.nlm.nih.gov/pubmed/24695708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3460-13.2014 |
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